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Standard dosing may be unsafe in these patients, necessitating individualized dose adjustments based on creatinine clearance or liver function tests

The growth phase (anagen) lasts years, and changes in nutrient status take months to visibly manifest in hair quality and density

On the other hand, endocrine fibroblast growth factor (FGF) analogs have emerged as a promising class because of their ability to not only act directly on liver, but also to shift whole-body metabolism to a healthier state