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The essential role of MEKK3 in TNF-induced NF-kappaB activation

A similar study investigated the protective effect of rooibos against methylbenzylnitrosamine-induced oesophageal cancer in male Fischer rats and reported that fermented and unfermented rooibos significantly reduced the number and size of papillomas, with rats drinking unfermented rooibos failing to develop larger papillomas [265,271]

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These results clearly demonstrated the effectiveness and reduced toxicity brought by the combination therapy, assisted by whole-cell catalysts that activate drugs at the disease site