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18 F-FDG-PET/MRI in preoperative staging of oesophageal and gastroesophageal junctional cancer"

That smoking is a major independent risk factor for coronary heart disease indicates that its effects cannot be entirely explained by changes in other risk factors and that it increases the incidence, development, and manifestation of cardiovascular disease by pathophysiologic mechanisms that are unique and relatively independent of dyslipidemia, hypertension, sex, or diabetes

Smoking appears to accelerate the loss of eggs and reproductive function and may accelerate the time to menopause by several years