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Outcome Focus: The trials were designed primarily to assess weight loss efficacy, with safety as a secondary outcome

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Food buffers the entire gastric compartment, dilutes SNAC concentration, and increases secretion of additional proteases, destroying the localized effect

Diagnostic Criteria and Phenomenology of Peripherally-Induced Movement Disorders Cardoso and Jankovic proposed the diagnostic criteria for PIMD, which has three core components: (a) severity of the trauma (should be severe enough to cause local symptoms for at least two weeks or requires medical evaluation within two weeks after trauma, (b) location of the trauma (body part with the involuntary movements should be anatomically related to the site of trauma, and (c) onset of the movement disorder (should be within days or months, up to one year after the injury) [ 2 , 16 ]