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NNMT is overexpressed in obese adipose tissue and is theorized to deplete SAM and NAD+ pools in adipocytes, contributing to metabolic dysfunction

Combining these supplements can be beneficial for individuals with deficiencies in one or both nutrients

Inflammation 48 , 485500 (2025)

Published preclinical literature also documents aod 9604 peptide research in lipogenesis inhibition suppression of new triglyceride formation providing a dual-action metabolic profile distinct from compounds affecting only one arm of fat metabolism