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gonorrhea has shown resistance to all antibiotics typically prescribed as first line treatments 33

Hospitals' measure results for Centers for Disease Control and Prevention (CDC) Central Line-Associated Bloodstream Infection (CLABSI), Catheter-Associated Urinary Tract Infection (CAUTI), Colon and Abdominal Hysterectomy Surgical Site Infection (SSI), Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, and Clostridium difficile Infection (CDI) are derived from standardized infection ratios (SIRs) calculated with hospital surveillance data reported to the CDC's National Healthcare Safety Network (NHSN) for infections occurring between January 1, 2021 and December 31, 2021

However, the combination treatment increased liver X receptor alpha (LXR), a nuclear receptor essential for bile acid synthesis, cholesterol efflux, and lipid metabolism regulation

It binds to these harmful compounds, facilitating their excretion from the body