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Therefore, in asthma, current smoking status and cumulative exposure to cigarette smoke are correlated with the development of persistent airflow obstruction over time

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Thus, it has been hypothesized that smoking is an effort to self-medicate in people with severe mental disorders (30), including BD, in terms of alleviating cognitive deficits (31), depression (32, 33) and reducing extrapyramidal symptoms associated with antipsychotic treatment

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