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doi: 10.1161/hs0302.103815 183 SunX.OuZ.ChenR.NiuX.ChenD.KangR.et al

In 1999 he was recruited to Harvard Medical School where his laboratorys research has focused primarily on understanding the role of sirtuins in disease and aging, with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer

(telomerase)Cell-culture work reporting telomerase induction and telomere elongation by the AEDG peptide

The deregulation of these genes along with other metabolism deregulation resulted in increased oxidative stress hence resulting in unrepairable DNA damage and reduced survival in glioma patients