glutathione synthetase deficiency symptoms in adults Sirona's Glutathione Synthetase Deficiency - StoryMD

( i ) Confocal images of mitochondria (imaged by TOM20 staining) and mtDNA in cells treated with 5FU for 72 h

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Doses typically start at 2 mg and increase gradually to 4, 8, or 12 mg over several weeks to help reduce the severity of side effects

Panickar et al., 2009), especially on the motor neurons (Koh et al., 2006) because it crosses the blood-brain barrier and modulates mitochondrial responses to OS (Table 1)