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You should discuss B12 testing and supplementation with your GP if you have risk factors such as long-term metformin use, restricted diet, significant weight loss, or symptoms of deficiency including neurological changes or unexplained fatigue

But B12 is involved in complex body wide set of interactions

Most patients notice improved sleep and recovery within the first 2 weeks

The consistently reported poor diagnosis and treatment experience encountered in UK Primary Care by people with a diagnosis, or symptomatic of, Pernicious Anaemia in the UK is well documented and reported on in research carried out and published by the Pernicious Anaemia Society