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In the intestine, if HDAC is overexpressed, the balance of gene expression is disrupted and cell proliferation is abnormal, which eventually leads to tumorigenesis (77)

10.3390/v8080210 53 LamN

Treatment with BA induces the nuclear translocation of NRF2, and its activation enhances the expression of NRAMP1, leading to increased phagosomelysosome fusion ( Figure 3 )