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Description

Mice were maintained in a temperature-controlled room (2122 C) on a 12 hr light/dark cycle and supplied with food and water ad libitum

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Ozempic) and chronic weight management (Wegovy)

Recent studies in mice have also shown that the repeated administration of insulin or GAD peptides, including the B923 peptide, can induce lethal anaphylactic responses (16, 17)