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Among these, data monitoring and collection emerged as the most prevalent application, featuring in 82 clinical trials and representing 31.3% of all included studies (Table 2)

XKR8 was initially identified as a caspase-3-activated phospholipid scramblase, primarily responsible for facilitating phosphatidylserine (PS) exposure, a classic hallmark of apoptosis 27,28

Discussion The control of Cys reactivity is of paramount importance in chemical biology research owing to the frequent use of its thiol functionality for protein synthesis as discussed in this work, but also for the site-specific modification of peptides or proteins

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