glutathion reductase

glutathion reductase Glutathione oxidized glutathione oxidoreductase Glutathione reductase - Wikipedia

Name: glutathion reductase Glutathione oxidized glutathione oxidoreductase Glutathione reductase - Wikipedia
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The nitrosoureas exhibit only partial cross-resistance with other alkylating agents, in Figure 14A-6, the diazonium hydroxide intermediate formed during BCNU hydrolysis decomposes to form a 2-chloroethyl carbonium ion (or equivalent), a strong electrophile, capable of alkylation of guanine, cytidine, and adenine bases

A comprehensive understanding of the TME is of the utmost importance because it provides valuable insights into pathways that could be targeted by novel metabolic therapies for advanced or drug-resistant cancers