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Antioxidants 12(9):1675 Kamio K, Azuma A, Ohta K, Sugiyama Y, Nukiwa T, Kudoh S, Mizushima T (2014) Double-blind controlled trial of lecithinized superoxide dismutase in patients with idiopathic interstitial pneumonia - short term evaluation of safety and tolerability

This chronic sympathetic activation not only causes anxiety, insomnia, and rapid heart rate, but it also signals to the innate immune system that the body is under constant threat, further provoking mast cell degranulation

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The GSH system, as a lipid peroxide scavenger, prevents the indefinite expansion of lipid peroxidation, which is a central step in hindering ferroptosis