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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Sotelo N., de los ngeles Durazo M., Gonzalez A., Dhanakotti N

Its core pathophysiological characteristics are intricately intertwined with abnormal iron and lipid metabolism, oxidative stress, mitochondrial dysfunction, and neuroinflammation, driving the progressive degeneration of dopaminergic neurons in the substantia nigra (SN) ( Figure 2 )

Saez et al., 2023)

Recent findings have indicated that the inhibition of glutamine metabolism can lead to a suppression of cancer cell apoptosis, a process that is believed to be influenced by the level of reactive oxygen species (ROS) metabolism