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Unconventional initiation of PINK1/Parkin mitophagy by Optineurin

doi: 10.1016/j.jmb.2008.03.019 42 KochMBhattacharyaSKehlTGimonaMVasakMChazinWet al

Feb 1999;22(2):233-240

Mechanism and Rapid Onset (Panel 1) : Succinylcholine triggers a Phase I depolarizing blockade by mimicking acetylcholine, leading to initial muscle fasciculations followed by prolonged membrane depolarization and flaccid paralysis