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Indeed, in more extreme cases with very aggressive inflammatory activity, a total reset of the patients immune system by autologous bone marrow transplantation has shown remarkable efficacy at stopping new relapses or MRI lesions and even modestly reversing clinical disability (Rush et al., 2019), though currently this aggressive intervention is recommended only for patients with very active inflammatory disease (Miller et al., 2021)

Some people may also suffer from pernicious anemia, which inhibits the body from being able to absorb enough vitamin B12, causing a deficiency

p 60K), Boston Pharmaceutical ( 60K), Boston Pharmaceutical ( 60K), Boston Pharmaceutical ( 0.67), with the MASEF score confirming 8 of these diagnoses, resulting in a concordance rate of 72.7%

People with chronic kidney or liver disease can accumulate B12 due to lower detoxification function when these organs are impaired