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while measurements in awake rats suggested that only about 50% of active brains energy requirements can be supplemented by -hydroxybutyrate even at saturating plasma concentrations (17mM) -- the rest has to derive from glucose oxidation (Chowdhury et al., 2014)

This work was supported by the French Government under the Investissements davenir (Investments for the Future) program managed by the Agence Nationale de la Recherche, (reference: Mditerrane Infection 10-IAHU-03)

Thus, the inhibition of this gene could play a role in reducing the virulence effect of pathogenic islands and act as a potential drug target for new antibiotic therapies, instead of the conventional antimicrobial modalities (Nammi et al., 2017)

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