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Phosphatidylcholine: Incorporated into all of your cell membranes to make them more fluid and function properly

and Crispe, N.J

Recent studies suggest that intestinal I/R injury may alter this delicate equilibrium, facilitating the passage of peripheral inflammatory signals to the brain, leading to neuroinflammation, and eventually compromising cognitive performance (Song et al., 2020

For example, Parkin, an E3 ubiquitin ligase encoded by the PRKN gene, ubiquitinates damaged mitochondria to induce degradation and mitophagy [38], and mutations in Parkin are the most common cause of autosomal recessive early-onset PD [38]