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Consider discussing B12 testing with your vet if your dog has: Had chronic or intermittent diarrhoea for more than a few weeks without a clear resolved cause Lost weight progressively despite adequate food intake Been diagnosed with a chronic gut condition, such as inflammatory bowel disease or exocrine pancreatic insufficiency A history of poor early nutrition, such as a recently rescued stray or previously malnourished dog Been through multiple courses of treatment for digestive symptoms without sustained improvement A young dog or puppy that is not developing or gaining weight as expected Causes of Vitamin B12 Deficiency in Dogs Vitamin B12 deficiency in dogs is almost always caused by a problem with absorption rather than a lack of B12 in the diet

Minor irritation or early-stage ulcers may respond more quickly, while chronic conditions, severe ulcers, or extensive tissue injury require longer periods for repair

10.19540/j.cnki.cjcmm.20210621.401 17 FanY.QianH.ZhangM.TaoC.LiZ.YanW.et al (2023)

However, some cohorts show no association or even contradictory trends depending on age, BMI, or genetic background