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This shows that DNA-TG does predict late leukopenia not only in NUDT15 nonvariants but also in NUDT15 variant patients highlighting the inclusive potential of DNA-TG measurements for patients with different ethnicities

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Additionally, a study showed that knockdown of CLEC16A, which encodes an E3 ubiquitin ligase that controls mitophagic flux in cells, impaired mitophagy, leading to the aggravation of apoptosis in cells treated with proinflammatory cytokines [110]