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Moreover, IL-10 production, a hallmark of M(Kp) polarization, has been reported to be governed by the TLR4MyD88CREB signaling pathway and is indispensable for intracellular bacterial survival (Li et al., 2025)

Decaffeinated coffee significantly reduced self-reported hunger compared with placebo across the full 180-minute window

2.5.2 Mechanisms of antimicrobial and defense action of systemin and prosystemin SYS and HypSYS peptides activate plant defense responses primarily through the JA signaling pathway