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Nicotine makes it difficult to give up due to withdrawal symptoms such as anxiety, frustration, decreased concentration, appetite and weight changes and headache

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The first article to discuss the links between cigarette smoking and lung cancer appeared in August 1951, summarizing a debate in the House of Commons where the Secretary of State for Health, Hilary Marquand, announced the Medical Committee (formed in 1948) would run the British Doctors Study to investigate further the suggested link between cigarette smoking and lung cancer because the statistics showed a massive increase in lung cancer related deaths from 1940