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doi: 10.1016/j.mito.2024.101975 121 MorrisGGevezovaMSarafianVMaesM

Pyruvate dehydrogenase kinase (PDK) phosphorylates and deactivates PDH, followed by the entrance of pyruvate to the lactic acid cycle

Moreover, the absorption maximum is roughly centered between the spectra observed for these states as they were assigned in Figure 3A suggesting the spectrum captured is a mixture of these states