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This is important, as pointed out by the FDA when they authorized the marketing of THS for sale in the U.S, because it is suggesting a likelihood that IQOS users may be able to completely transition away from combustible cigarettes and use IQOS exclusively

By the end of the decade, marketing menthols to the general (aka white) population was done practically as an afterthought, as so much effort was focused on not just securing the Black consumer base, but expanding it by any means necessary

Collider bias may occur when analyses are controls or selects the sample based upon a collider variable that is caused by both the exposure and outcome variables and distorts the true underlying association 48,49

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