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Meantime, hepatic and renal function biochemical markers tests exhibited normal ranges of values in the PBS, Gi-F-CAA (8 mg/kg in 100 L PBS), Gi-F-CAA (12 mg/kg in 100 L PBS) and Gi-F-CAA (16 mg/kg in 100 L PBS) treatment groups at 1 day post-injection, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), urea nitrogen (BUN), and creatinine (CRE) levels (Supplementary Fig

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28 Further, it transformed into water in the presence of catalytic enzymes like glutathione peroxidases (GPx) and peroxiredoxins

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When this happens, your hair can be one of the first things to show signs of deficiency, with increased shedding, thinning or premature greying

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Additionally, the extravasation of immune cells, particularly neutrophils and monocytes, further amplifies the astrocyte activation process through the release of proinflammatory cytokines and chemokines (54)

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