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IL-6 induced apoptosis was significantly higher than TNF-, IFN-, NAC, IL-6 + NAC, TNF-+NAC and IFN-+NAC (Fig

(Table 6)

Finally, to test whether the accumulated lipids must be sequestered into lipid droplets to exert their protective effect, we disrupted lipid droplet formation by knocking down Perilipin-2 (PLIN2), a key structural protein involved in lipid droplet maintenance 37