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Importantly, however, particle design governs risk: surface-displayed antigens or certain chemistries can raise immunogenicity and, in rare cases, provoke severe hypersensitivity (including anaphylaxis), whereas encapsulation strategies tend to blunt immediate antigen recognition and are therefore often safer in vivo (206, 208)

Specifically, it decarboxylates G6P and forms ribose-5-phosphate (R5P) via three irreversible reactions

Wear proper footwear Avoid high heels and opt for supportive shoes

Novel economic incentives and policies must be enacted to revitalize depleted antibiotic product development and prioritize using essential drugs for the most critical resistant pathogens [28]