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Enhancing ferroptosis requires the inhibition of system Xc, depletion of GSH, and deactivation of GPX4 (Yang et al., 2014)

They conducted a pioneering study in which they used aminopterin, one of the above-mentioned intermediates, to induce clinical remission in patients with ALL (8)

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Immunofluorescence staining Interventions in different groups were repeated as described above after NPCs were seeded in a 24-well plate (3 10 4 cells/well)