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Using NRTs in conjunction with a comprehensive quit plan increases the chances of successfully quitting smoking

Consequently, they should not answer exactly as healthy cells would do, making them a poorly reliable representation of what really occurs in vivo

The meta-analytic tool overcomes many of the limitations of traditional meta-analyses by incorporating between-study heterogeneity into the uncertainty of risk estimates, accounting for small numbers of studies, relaxing the assumption of log(linearity) applied to the risk functions, handling differences in exposure ranges between comparison groups, and systematically testing and adjusting for bias due to study designs and characteristics

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