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Elamipretide reduces IPF-associated inflammation and fibrosis by inhibiting Nrf2-dependent NLRP3 inflammasome in macrophages (274)

Methods: We employed keywords such as TCM, TM, Botanical drug, HACE, and Hypoxia to systematically retrieve studies on the therapeutic use of TCM and TM for HACE published up to May 2025, in databases including Web of Science, PubMed, China National Knowledge Infrastructure (CNKI) and Wanfang Data

Anti-inflammatory and antioxidant effects: GHK-Cu downregulates pro-inflammatory cytokines (like IL-6) and upregulates antioxidant enzymes (such as superoxide dismutase)

This process of the birth and development of neurons is called neurogenesis.(2) Neurogenesis helps form neurons in the brain, which are important in the development of embryos throughout their lifespans.(3) For example, in the adult brain, there are 27 different types of neurons located in the hippocampus, the brain region responsible for spatial navigation and memory, alone