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Sublingual B12 is generally very safe with minimal side effects

Quick reference for 5 mg/mL concentration (2 mL water in 10 mg vial) If you followed the recommended 2 mL reconstitution, every calculation becomes simple: 1 mg dose = 20 units (0.2 mL) 2 mg dose = 40 units (0.4 mL) 2.5 mg dose = 50 units (0.5 mL) 3 mg dose = 60 units (0.6 mL) 4 mg dose = 80 units (0.8 mL) 5 mg dose = 100 units (1.0 mL) See the pattern

In clinical settings in Russia, Selank received registration as an anxiolytic medication and has been used for generalized anxiety disorder and neurasthenia

This raises the question: would different GLP-1 formulations or compounds with better CNS penetration show benefit