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demonstrated that the X protein of HBV enhances the binding of transcription factors NF-B and cAMP-response element-binding protein to the promoter of the MAT2A gene, and thus regulates its expression, which is essential in HBV-mediated HCC progression

Among them, TP53 exerts a context-dependent dual role in ferroptosis regulation 153

Importantly, along with an induction of HIF1, in SCD erythroblasts cultured in the absence of hemin, we detected a significantly decreased CBS expression under hypoxia compared to normoxia (Supplementary Fig