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We applied an unsupervised principal component analysis (PCA) to assess class (genotype and/or treatment) homogeneity and to identify outliers, and then, we used a supervised OPLS-DA (orthogonal partial least squares discriminant analysis) to evaluate class discrimination and highlight metabolic differences associated with Tbx1 mutation

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However, a further reduction in payment has the potential to create access issues for the vulnerable patient population of patients with intractable epilepsy in whom these neurostimulator are utilized

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