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Furthermore, Shamansoori et al

Evidence showed that fatty acid synthesis is markedly upregulated during differentiation of primary human monocytes, and its inhibition reduces macrophage phagocytosis, which can be fully rescued by supplementation with a fatty acid-CoA mixture (34)

97 IDA's complex pathogenesis might be driven by a lowered erythropoietin response, decreased RBC survival along with reduced iron absorption and macrophageal iron retention, limiting iron delivery to erythroid precursor cells