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Indeed, the rise of endogenous GSH leads to elevated SA levels ( PR-1a in foliar tissues ( PR-1 expression was also observed in a lesions simulating disease ( lsd ) mutant of Arabidopsis thaliana that spontaneously develops HR-like necrotic lesions ( PR-1a expression to a similar extent as SA, in both Xanthi NN and SA-deficient NahG leaves, although gene induction is slower and less pronounced in NahG plants ( Figure S3 )

170 Benefitting from the role of ATP in the activation of inflammatory bodies, one feasible target could be focused on the intervention of ATP in regulating inflammatory response as well as inflammation-related diseases