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For instance, in glucose-deficient glioblastoma, heightened SLC7A11 expression leads to the generation of ROS and oxidative stress through the consumption of intracellular NADPH during the conversion of imported L-cystine to L-cysteine ( in vivo , within a tumor microenvironment, where the metabolic reprogramming associated with altered SLC7A11 expression was evident ( in vivo experiments demonstrated that heightened SLC7A11 expression facilitated localized tumor growth while impeding tumor migration

Genomics and transcriptomics can analyze the functional genes and expression profiles of gut microbiota, uncovering microbial metabolic potential and its connection to fatty acid metabolism [199]

Optimal cholesterol management is important for risk reduction, but so is managing the several other established cardiovascular disease risk factors

In contrast, due to the vertical distribution of the *OOH intermediate at the Ru site on Ru-oxide, the H atom on *OOH is unfavorable for the interaction with the Ru site, resulting in unfavorable decomposition of *OOH on Ru-oxide (Fig