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S -(1,2-Dichlorovinyl)-L-cysteine-induced apoptosis also has been reported in primary cultures of human proximal tubule cells (Lash et al

Metabolic networks in ferroptosis

Modifying the carrier surface with targeting molecules such as aptamers or functional peptides can improve local drug retention and specificity in diseased cartilage or pathological synovial cells, while reducing potential adverse effects from systemic exposure

10 Even if an antibiotic does have the appropriate characteristics making it a good candidate for systemic absorption, the characteristics of the suppository vehicle can still impact rate and extent of drug release, and therefore bioavailability