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These results suggested that keloid fibroblasts underwent pro-senescence regulation earlier compared with normal skin fibroblasts via p53-pS15 under serum limitation stimulus, and p53-pS15 and FOXO4 translocated from the nucleus to the cytoplasm during FOXO4-DRI treatment

Cartilage & Joint Protection Because DSIP is often studied for sleep regulation , it is natural to compare it with melatonin , the most widely used sleep supplement: AOD-9604 demonstrated chondroprotective effects in models of cartilage degradation. May reduce proteoglycan loss and support collagen maintenance