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# The Orange Book was initially intended as a resource to provide medical professionals with a list of approved drugs and their corresponding therapeutic equivalents

Acknowledgements The authors are supported by NIH grants R01 NR014852 and R01NS096008

The erratic nerve signaling that causes the rapid heart rate and blood pressure swings in POTS is worsened by the lack of antioxidant protection in the central nervous system

Coben said, Its a thrill to be reunited with my former long-time editor, Ben Sevier, and Im looking forward to working with the entire Grand Central Publishing team. Sevier, who edited Cobens ten consecutive #1 New York Times bestsellers between 2007 and 2017, said of the acquisition, Ive known Harlan Coben for two decades, first as a fan and then as his editor and publisher