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R 0 represents viral transmissibility, indicating an average number of new infections transmitted by an infected individual in a totally nave population

Graying occurs when the melanocytes (cells responsible for hair color) stop producing melanin or when hydrogen peroxide builds up in the hair follicle, essentially "bleaching" the hair from the inside out

ATP release through connexin hemichannels depletes intracellular ATP, leading to necrosis and inflammation (Kalvelyte et al

Addressing these mechanisms requires advanced methodologies, including single-cell multi-omics and spatial transcriptomics, to dissect the interplay between innate and adaptive compartments at lesion sites