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Publication bias was judged by Begg's funnel plot and Egger's test ( trim and fill approach was applied in the case of an asymmetrical funnel plot to adjust for the potential publication bias ( Results Flow and Characteristics of Included Studies We identified 330 records through the literature search

Lo Bello M, Battistoni A, Mazzetti AP, Board PG, Muramatsu M, Federici G et al

In fact, in mice, depletion of the mitochondrial transcription factor A (TFAM), which controls transcription, replication and 3D structure of the mitochondrial genome, caused the activation of the cGAS-STING inflammatory pathway