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TNF--induced optic nerve degeneration and nuclear factor-B p65

While ferroptosis helps eliminate infected or damaged cells, its dysregulation exacerbates inflammation, tissue injury, and alveolar-capillary barrier dysfunction in ARDS ( 2.2 Key molecular mechanisms of ferroptosis Ferroptosis is characterized by the iron-dependent accumulation of lipid peroxides, driven by dysregulated oxidative stress and impaired antioxidant defenses

Furthermore, when PBMCs from healthy controls were suspended in plasma from ME/CFS patients, the impedance pattern resembled that of ME/CFS patients [1]

The GBA1 gene encodes the lysosomal enzyme, glucocerebrosidase