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Targeting gp130 to prevent inflammation and promote insulin action

10.2174/1871520621666211119085834 84 TungY

Annu Rev Nutr 27:1940

They not only directly inhibit tumor cell proliferation and induce apoptosis but also, more importantly, potently activate DCs, promoting their maturation and antigen-presenting function, thereby laying the foundation for cytotoxic T-cell activation [272,273,274,275]