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725 A randomized clinical trial has found that intravenous administration of the iron-chelating agent DFO reduces systemic iron levels and may have long-term efficacy in patients with ischemic stroke

It is noteworthy that VEGF overexpression favors neovascularization accompanied by plasma leakage but Ang-1 overexpression favors enlargement of existing blood vessels without favoring plasma leakage [146]