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Recent studies have demonstrated that soluble dietary fiber can alleviate alcohol-induced liver injury in mice by regulating conjugated bile acid levels in the gut through Bacteroides acidifaciens , thereby modulating the FXR-FGF15 signaling pathway [211]

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Patients with pre-existing B12 deficiency (serum levels 400 pg/mL) and liver function is healthy, the lipotropic components provide minimal standalone benefit without concurrent dietary modification