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Persistently low B12 levels can cause pernicious anemia, stomach problems or nerve damage

FIGURE 6 Activation of Adaptive Stress Responses by AQ-QI and DEAQ-QI and Effects of GSTP1 The stress responses induced by AQ-QI and DEAQ-QI exposure were measured with a high-content image-based BAC-GFP stress responses reporter assay for oxidative stress, ER stress, DNA damage stress and inflammatory stress (Wink et al., 2014, 2017)

The presence of TSab is characteristic of active GD, and if the thyroid can respond (e.g., has not been ablated with RAI), hyperthyroidism ensues