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found that pristimerin can enhance the expression and binding ability of Nrf2, increase the transcriptional expression of HO-1, and have a protective effect on ConA-induced hepatitis (Figure 5) ( Primary Biliary Cholangitis (PBC) PBC, also known as primary biliary cirrhosis, is a chronic cholestatic disease caused by chronic progressive non-purulent inflammation of the small bile ducts in the liver

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In some people, particularly older adults or those with limited protein intake, both glycine and cysteine availability may constrain glutathione synthesis

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