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Documented Long-Term Side Effects of NSAIDs Regular or long-term NSAID use has been associated with: Damage to the gut lining, increasing intestinal permeability (leaky gut) and immune activation (27,29,31) Reduced absorption of key nutrients, including iron, folate, and vitamin C (28,29) Delayed tissue repair , particularly in connective tissue where prostaglandins are required for healing (32) Kidney stress and electrolyte imbalance , especially during dehydration or endurance activity (30) Increased cardiovascular risk , particularly with higher doses or prolonged exposure (30) These effects help explain why NSAIDs may temporarily reduce pain while progressively impairing healing capacity, increasing systemic inflammation, and slowing long-term recovery

A., Gelmon, K., Mayer, L

Molecular Characteristics BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a partial sequence of a naturally occurring protective protein identified in human gastric juice

Patients who complete two or three cycles consistently report that the improvement between cycles two and three is greater than the improvement between baseline and cycle one